METHOD OF CORRECTION AND PREVENTION OF OSTEOPOROSIS osteoporotic fractures resveratrol IN COMBINATION WITH ENALAPRIL

摘要

FIELD: medicine.;SUBSTANCE: efficacy is studied in female Wistar rats. Osteoporosis is simulated by bilateral ovariectomy. Osteoporosis is corrected by intraperitoneal introduction of reservatrol 2 mg/kg and intragastric introduction of enalapril 0.5 mg/kg daily once a day for eight weeks after ovariectomy. Osteoprotective action of reservatrol combined with enalapril is estimated by a bone tissue microcirculation level and width of trabeculas of bone.;EFFECT: improved blood circulation and microarchitectonics of bone tissue in hypoestrogen condition.;1 tbl, 2 ex