APPLICATION OF COMPLEMENT PATHWAY INHIBITORS FOR TREATMENT OF EYE DISEASES

摘要

FIELD: medicine.;SUBSTANCE: group of inventions refers to medicine, namely to ophthalmology, and can be used in treatment of eye diseases. The methods under the invention include the introduction of a complement pathway inhibitor with C2a, C3a, C5, C5a, C5b, C7, C8 or C9 inactivation. Also, the methods under the invention concern the inhibition of an alternative complement pathway by introducing Factor H or its functional peptide, or siRNA specific for a complement pathway protein, or nucleic acid coding the complement pathway inhibitor.;EFFECT: use of the inventions allows treating eye diseases due to inactivating the classical and alternative complement pathways.;39 cl, 1 ex