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method for the preparation of cd10 activated prodrug compounds

机译:cd10活化前药化合物的制备方法

摘要

The compounds of the invention are modified forms of therapeutic agents. A typical prodrug compound of the invention comprises a therapeutic agent, an oligopeptide, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by the CD10 enzyme. Methods of treatment using the prodrug and methods of designing a prodrug are also disclosed.
机译:本发明的化合物是治疗剂的修饰形式。本发明的典型前药化合物包含治疗剂,寡肽,稳定基团和任选地连接基团。前药可被CD10酶裂解。还公开了使用前药的治疗方法和设计前药的方法。

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