SINGLE USE OR COMBINATIONAL USE OF SEX STEROID PRECURSOR AND SELECTIVE ESTROGEN RECEPTOR MODULATOR FOR PREVENTING AND TREATING VAGINAL ATROPHY, ATROPHIC VAGINITIS AND VAGINAL DRYNESS IN POSTMENOPAUSAL WOMEN

摘要

PROBLEM TO BE SOLVED: To provide an effective method for treating problems with vaginas which reduce a sexual craving and a sexual act with bringing unwanted side-effects to be minimum, more precisely for treating the vaginal dryness, the dyspareunia and the sexual impairment.SOLUTION: There is provided the use of a sex steroid precursor selected from the group consisting of dehydroepiandrosterone, dehydroepiandrosterone sulfate, androst-5-en-3, 17-diol and 4-androsten-3,17-dione for producing a pharmaceutical agent treating or reducing possibility to be problems affecting the proper layer and/or muscular layer of the vaginas in postmenopausal women, wherein the problems are vaginal atrophy, atrophic vaginitis and vaginal dryness.