首页> 外国专利> Novel phenylacetate derivative or pharmaceutically acceptable salt thereof, process for producing the same, and composition for preventing or treating diseases induced by the activity of T-type calcium ion channel containing the same as an active ingredient

Novel phenylacetate derivative or pharmaceutically acceptable salt thereof, process for producing the same, and composition for preventing or treating diseases induced by the activity of T-type calcium ion channel containing the same as an active ingredient

机译:新型苯乙酸酯衍生物或其药学上可接受的盐,其制备方法以及用于预防或治疗由包含其作为活性成分的T型钙离子通道活性引起的疾病的组合物

摘要

Disclosed herein are a new phenylacetate derivative represented by Chemical Formula 1 or pharmaceutically acceptable salt thereof, a preparation method thereof, and a composition for prevention or treatment of diseases induced by the activation of T-type calcium ion channels containing the same. The composition containing the phenylacetate derivative according to the present invention effectively inhibits the activation of T-type calcium ion channels and may be useful in the prevention or treatment of diseases such as hypertension, cancer, epilepsy, and neurogenic pains induced by the activation of T-type calcium ion channels. wherein, X, R1, and R3 are as defined herein.
机译:本文公开了由化学式1表示的新的苯乙酸酯衍生物或其药学上可接受的盐,其制备方法以及用于预防或治疗通过活化包含其的T型钙离子通道引起的疾病的组合物。根据本发明的包含苯乙酸酯衍生物的组合物有效地抑制T型钙离子通道的活化,并且可用于预防或治疗由T的活化引起的疾病,例如高血压,癌症,癫痫和神经性疼痛。型钙离子通道。其中,X,R 1和R 3如本文所定义。

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