TRANSDERMAL THERAPEUTIC SYSTEM CONTAINING TULOBUTEROL HYDROCHLORIDE FOR ADMINISTERING BRONCHODILATOR TULOBUTEROL VIA SKIN

摘要

PROBLEM TO BE SOLVED: To provide a transdermal absorbable medicinal preparation of tulobuterol.SOLUTION: The transdermal therapeutic system includes: a largely water vapor-impermeable backing layer; at least one matrix layer containing tulobuterol as an active substance; and a removable protective layer, wherein the matrix is built up on the basis of polyacrylate pressure-sensitive adhesive and, as an active substance, tulobuterol is included in the form of its salt, tulobuterol hydrochloride. In addition, as a permeation enhancing additive, one or more kinds of fatty acids, preferably, lauric acid, myristic acid or oleic acid are added in the matrix layer.