USE OF IL-1 INHIBITOR AND TNF ANTAGONIST PARTIALLY IN COMBINATION WITH RECOMBINANT ERYTHROPOIETIN FOR ANAEMIA THERAPY

摘要

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition effective for treating blood disorder in mammals.SOLUTION: Therapeutically effective amount of a pharmaceutical composition contains an interleukin-1 (IL-1) inhibitor and use thereof. In addition, a therapeutic method for blood disorder in mammals uses an IL-1 inhibitor, a TNF inhibitor and an erythropoietin (EPO) receptor agonist. The invention also relates to an IL-1 inhibitor composition, and a composition of the IL-1 inhibitor, the TNF inhibitor and the EPO receptor agonist.