The methods and compositions in the detection of particle-based of the target molecule using a shared bond-forming reaction pair

摘要

The disclosed compositions and methods can be used to increase the probability and / or intensity to form a binding complex comprising a substrate and a target molecule. In one embodiment, a linking molecule that has to be used to increase the composite body binding interactions in complex comprising a substrate and a target molecule, members of one or more of the reaction pair is disclosed. It is possible to use a complex between the cross-linking and within the complex cross-linking in connection with the methods and compositions thereof, and to further strengthen the binding complexes that have been disclosed, to stabilize.