Immunology analysis method and its utilization null of methylation heterojiniasu nukurea

摘要

PROBLEM TO BE SOLVED: To provide a tumor marker capable of simultaneously detecting a few types of cancers and perform early detection of cancers.;SOLUTION: An anti-hnRNP antibody and an antibody which binds with an anti-methylated amino acid residual group are used to analyze methylated hnRNP groups in blood of cancer patients, have found that methylated hnRNP groups have also increased in blood of colon cancer patients, and further that methylated hnRNP groups have also increased in blood of patients of lung cancer and breast cancer, cancers different from colon cancer, in comparison with those of healthy persons. It is thereby possible to detect cancers such as colon cancer, lung cancer, and breast cancer by a methylated hnRNP immunological assay method using an antibody which binds with a methylated amino acid residual group and detect cancer at a high ratio even in blood of patients of not only advanced cancer and terminal cancer but also early-stage stage-I cancer of which symptoms are not apparent.;COPYRIGHT: (C)2008,JPO&INPIT