Its use vectors and use the Borna disease virus

摘要

Untranslated region within which has the same order in the Borna disease virus genome, N gene, X gene, the L gene and the P gene, it is connected to the downstream of the translation region of the P gene at least in (a) Borna disease virus genome cDNA of the recombinant viral RNA having a sequence foreign gene is inserted into, and a (c) a promoter sequence and encoding DNA (b) a ribozyme, (b) is arranged upstream and downstream said of (a) , and viral vectors generating means and (a) (b) is located downstream of (c).