首页> 外国专利> Novel serotype of Lawsonia intracellularis bacterium, vaccine based on the bacterium, antibody suitable for identification of the novel Lawsonia intracellularis serotype, and hybridoma for producing the antibody

Novel serotype of Lawsonia intracellularis bacterium, vaccine based on the bacterium, antibody suitable for identification of the novel Lawsonia intracellularis serotype, and hybridoma for producing the antibody

机译:新型胞内劳森菌血清型,基于该细菌的疫苗,适用于鉴定新型胞内劳森菌血清型的抗体以及用于产生该抗体的杂交瘤

摘要

This invention pertains to Lawsonia intracellularis bacterium of a serotype which is reactive with monoclonal antibody INT-LIC-02-02 as produced by hybridoma INT-LIC-02-02 deposited with the Collection Nationale de Cultures de Micro-organismes of the Institut Pasteur at Paris France under nr. CNCM I-4049 but which is not reactive with antibody INT-LIC-01-28 as produced by hybridoma INT-LIC-01-28 deposited with the Collection Nationale de Cultures de Micro-organismes of the Institut Pasteur at Paris France under nr. CNCM I-4048. The invention also pertains to vaccines for protection against an infection with Lawsonia intracellularis based on those novel bacteria, antibodies suitable for diagnosing the novel Lawsonia intracellularis serotype and hybridomas for producing the said antibodies.
机译:本发明涉及一种血清型胞内劳森菌,它与单克隆抗体INT-LIC-02-02有反应,该单克隆抗体是由保藏于巴斯德研究所国家微生物保藏中心的杂交瘤INT-LIC-02-02产生的。法国巴黎CNCM I-4049,但不与杂交瘤INT-LIC-01-28产生的抗体INT-LIC-01-28发生反应,杂交瘤INT-LIC-01-28保藏在法国巴黎巴斯德研究所微生物保藏中心,编号为nr。 CNCM I-4048。本发明还涉及基于这些新型细菌的用于防止细胞内劳森菌感染的疫苗,适用于诊断该新型细胞内劳森菌血清型的抗体和用于产生所述抗体的杂交瘤。

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