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Novel potassium channel and gene encoding the potassium channel

机译:新型钾通道和编码钾通道的基因

摘要

This invention relates to novel potassium channels and genes encoding these channels. More specifically the invention provides isolated polynucleotides encoding the KCNQ5 potassium channel subunit, cells transformed with these polynucleotides, transgenic animals comprising genetic mutations, and the use of the transformed cells and the transgenic animals for the iin vitro/i and iin vivo/i screening of chemical compounds affecting KCNQ5 subunit containing potassium channels.
机译:本发明涉及新的钾通道和编码这些通道的基因。更具体地说,本发明提供了编码KCNQ5钾通道亚基的分离的多核苷酸,用这些多核苷酸转化的细胞,包含遗传突变的转基因动物,以及转化的细胞和转基因动物在体外和<在体内筛选影响含有钾通道的KCNQ5亚基的化合物。

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