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Methods for analyzing lipids and membrane proteins in biological matter using stable isotopes and mass spectrometry
Methods for analyzing lipids and membrane proteins in biological matter using stable isotopes and mass spectrometry
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机译:使用稳定同位素和质谱分析生物物质中脂质和膜蛋白的方法
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摘要
Methods for accurately comparing the levels of ionizable lipids in two cell populations that differ in some respect from each other using mass spectroscopy and isotopic labeling are provided. The methods can be used to identify a change in a lipid of interest in response to a cellular, chemical, genetic, or environmental change to the cell population (i.e., a lipid response to a cell perturbation). The change in the lipid of interest can be a change in composition, rate of synthesis, and/or location of the lipid.
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