PREPARATION METHOD OF HYDROXYAPATITE COATING LAYER USING AEROSOL DEPOSITION AND HYDROTHERMAL TREATMENT, AND NANOSTRUCTURED HYDROXYAPATITE COATING LAYER PREPARED BY THE METHOD

摘要

A method of preparing a nano-structured hydroxyapatite [Ca₁₀(PO₄)₆(OH)₂, HA] coating layer with improved biocompatibility is provided. The preparation method includes: (S1) putting hydroxyapatite [Ca₁₀(PO₄)₆(OH)₂, HA] powder in a powder chamber, placing a metal substrate in a deposition chamber, and keeping the chamber in vacuum state by using a vacuum pump; (S2) injecting carrier gas into the powder chamber and mixing with hydroxyapatite powder; (S3) spraying the mixture of the powder and the carrier gas onto the surface of metal substrate in the deposition chamber through a nozzle and depositing hydroxyapatite coating layer on the metal substrate; (S4) hydrothermal-treating the deposited hydroxyapatite coating layer; and (S5) rinsing the hydrothermal-treated hydroxyapatite coating layer and drying the layer. Additionally, a thermal-treated, nano-structured hydroxyapatite [Ca₁₀(PO₄)₆(OH)₂, HA] coating layer with improved biocompatibility fabricated by the above preparation method is provided.