Preparation method of hydroxyapatite-chitosan composite coating layer using aerosol deposition and hydroxyapatite-chitosan composite coating layer with enhanced bioactivity

摘要

The present invention relates to a method for preparing an apatite hydroxide-chitosan composite powder coating layer using an aerosol deposition method, and to an apatite hydroxide-chitosan composite powder coating layer having improved bioactivity, and more particularly, to heat treating an apatite hydroxide raw material powder ( Step 1); Dry milling the apatite hydroxide powder and chitosan powder heat-treated in step 1 to prepare a composite powder (step 2); And it provides a method for producing a biologically enhanced apatite-chitosan composite powder coating layer comprising the step (step 3) of coating the apatite hydroxide-chitosan composite powder prepared in step 2 on the substrate by aerosol deposition. Apatite hydroxide-chitosan composite powder according to the present invention can be prepared by a simple dry mixing, the composite powder is coated on a substrate at room temperature by aerosol deposition method, dense, excellent adhesion and improved bioactivity Apatite-chitosan composite powder coating layer Since it is provided, it can be usefully used for medical implants.;Apatite Hydroxide, Chitosan, Aerosol Deposition, Implants