1,2,4-triazolo4,3-cpyrimidin-3-one and pyrazolo4,3-e-1,2,4-triazolo4,3-cpyrimidin-3-one compounds for use as adenosine A_2a receptor antagonists

摘要

Compounds of the Formula I wherein R¹ and R² together with the carbon atoms to which they are bonded optionally form a further heteroaromatic ring of the formula (II) as well as pharmaceutically acceptable salts, solvates, esters and prodrugs thereof are adenosine A2a receptor antagonists and, therefore, are useful in the treatment of central nervous system diseases, in particular Parkinson's disease.;