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TRANSLATION FACTORS AS ANTI-AGING DRUG TARGETS
TRANSLATION FACTORS AS ANTI-AGING DRUG TARGETS
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机译:翻译因素作为抗衰老药物的目标
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摘要
In certain embodiments this invention pertains to the discovery that inhibition of the expression and/or activity of eukaryotic initiation factor 4A (eIF4A) inhibits the aging process. Accordingly, in certain embodiments, methods are provided for inhibiting/slowing aging. The methods typically involve administering to a mammal an agent that inhibits the expression and/or activity of eukaryotic initiation factor 4A (eIF4A) in an amount sufficient to inhibit expression or activity of EIF4A, where the agent is not resveratrol.
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