humanized anti-interleukin-18 antibody, pharmaceutical composition, use of an anti-interleukin 18 antibody, and methods of treating a human patient afflicted with an autoimmune disease, producing an antibody and selecting an antibody

摘要

HUMANIZED ANTIBODY-18 ANTIBODY, PHARMACEUTICAL COMPOSITION, USE OF AN ANTI-INTERLEUKIN ANTIBODY 18, AND METHODS OF TREATMENT OF A HUMAN PATIENT, AFFECTED WITH AN AUTOMUNE DISEASE, PRODUCTION OF AN ANTIBODY SELECTION AND The invention describes humanized anti-IL-18 antibodies, manufacturing methods and methods of treating said antibodies. Screening methods using, for example, surface plasmon resonance to identify antibodies with therapeutic potential are further described.