MTOR Kinase Inhibitors for indicators of Oncology and diseases associated with PI3K / Akt / mTOR Pathway

摘要

Heteroaryl compounds are provided in the present which have the following Structure: wherein R1 - R4 are as defined herein, compositions comprising an effective amount of a heteroaryl compound and Methods for treating or Preventing cancer, inflammatory conditions, padecimient Os immunological, diabetes, obesity, Neurodegenerative Diseases, Neurological Disorders,Age related disease, or cardiovascular disease, comprising administering an effective amount of a heteroaryl Compound to a patient in need.