ANTI- CD20 ANTIBODY, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND USES THEREOF IN THE PREPARATION OF MEDICAMENTS FOR THE TREATMENT OF LYMPHOMA OR RHEUMATOID ARTHRITIS

摘要

The present invention provides polypeptides, particularly therapeutic antibodies, comprising a novel, variant Fc region. Furthermore the invention provides variant Fc regions which confer an altered effector function or altered serum half life upon a polypeptide to which it is operable attached.