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PROCESS FOR THE PREPARATION OF A 1-PHENYL-2-OXA-TRIAZATRIDECAN-13-OIC ACID FOR USE AS A DIAGNOSTIC CONTRAST AGENT
PROCESS FOR THE PREPARATION OF A 1-PHENYL-2-OXA-TRIAZATRIDECAN-13-OIC ACID FOR USE AS A DIAGNOSTIC CONTRAST AGENT
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机译:用作诊断对比剂的1-苯基-2-氧杂-三氮杂十三烷十三-Oic酸的制备方法
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摘要
The present invention refers to a process for preparing a compound of formula (I) through a carboxymethylation reaction occurring in the presence of a suitable alkylating agent and of a base, without the need of monitoring the pH of the reaction environment. The compound of formula (I) is a useful intermediate in the preparation of diagnostic contrast agents for MRI techniques.
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