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Triiodized isophthalic acid diamides useful as shading agents in X-ray contrast agents, their preparation process and X-ray contrast agents containing them.
Triiodized isophthalic acid diamides useful as shading agents in X-ray contrast agents, their preparation process and X-ray contrast agents containing them.
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机译:三碘化间苯二甲酸二酰胺可用作X射线造影剂,其制备方法和含有X射线造影剂的遮光剂。
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摘要
New triiodinated isophthalic acid diamides of the formula IMAGE wherein the amide residues -CO-N.R1R2 and -CO-N.R3R4 are different from each other and R1 is hydrogen or C1-6 alkyl, R2 is mono- or polyhydroxyalkyl, R3 is hydrogen or C1-6 alkyl, R4 is mono- or polyhydroxylalkyl, R5 is C1-6 alkyl or mono- or polyhydroxy-C1-6-alkyl or C1-3-alkoxy-C1-3-alkyl, and R6 is hydrogen, C1-6 alkyl or mono- or polyhydroxyalkyl provide superior nonionic X-ray contrast media.
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