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METHOD FOR PRODUCING OPTICALLY ACTIVE, CYCLIC DEPSIPEPTIDES COMPRISING LACTIC ACID AND PHENYL LACTIC ACID AND HAVING 24 RING ATOMS, USING FUNGUS STRAINS OF ROSELLINIA TYPE, AND FURTHER SPECIES OF XYLARIACEAE
METHOD FOR PRODUCING OPTICALLY ACTIVE, CYCLIC DEPSIPEPTIDES COMPRISING LACTIC ACID AND PHENYL LACTIC ACID AND HAVING 24 RING ATOMS, USING FUNGUS STRAINS OF ROSELLINIA TYPE, AND FURTHER SPECIES OF XYLARIACEAE
The present invention relates to a process for the preparation of lactic- and phenyllactic-acid-containing, optically active, cyclic depsipeptides with 24 ring atoms by means of fungal strains of the genus Rosellinia and further Xylariaceae isolated not only from fruiting bodies of Rosellinia spp. and Xylariaceae growing on dead timber and live timber of deciduous and coniferous trees, but also directly from timber and roots of deciduous and coniferous trees, or by means of enzymatic preparations isolated from these fungal strains. PF1022A, of the general formula (I), is outstandingly suitable for controlling endoparasites, in particular in the field of medicine and veterinary medicine.
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