Novel oil in water emulsion vaccine formulations comprising polyoxyethylene-polyoxyproplene block copolymer, mineral oil and a non-ionic hydrophilic ethoxylated fatty alcohol

摘要

Disclosed is an oil-in -water (O/W) emulsion comprising: (1) an aqueous solution containing a vaccine antigen or immunogen capable of inducing an immune response in a host; (2) A non-ionic lipophilic surfactant which is polyoxyethylene-polyoxypropylene block copolymer (POE-POP block copolymer); (3) A mineral oil; and (4) A non-ionic hydrophilic ethoxylated fatty alcohol.