首页> 外国专利> N-phenyl compounds (piperazinil u homopiperazinil) - benzofuran or benzofuran phenyl compounds (piperazina or homopiperazine) as serotonin receptor modulators

N-phenyl compounds (piperazinil u homopiperazinil) - benzofuran or benzofuran phenyl compounds (piperazina or homopiperazine) as serotonin receptor modulators

机译:N-苯基化合物(哌嗪腈或高哌嗪腈)-苯并呋喃或苯并呋喃苯基化合物(哌嗪嗪或高哌嗪)作为血清素受体调节剂

摘要

A herbicide or homoherbicide derivative from formula (I) or (I),Where x is link or n-r4; R1 is h or methyl; R2 is h or methyl; R3 is h, C1-C3 tar, fluorine, etc.; R4 is h, C1-C4 tar, C3-C4 cyclopropyl compound, etc.; R5 is h, F, Cl, C1-C2 tar, etc.; R6 is h, f or Cl; n is 1 or 2. The most popular are: n - (3-chlorofluoromethane-phenyl) - 4-methyl-3-piperazin-1-il-benzofuran, 1 - [5 - (3-difluoromethane-benzofuran) - 2-methyl-phenyl) hydrochloride, N - (4-difluoromethane-phenyl) - 4-methyl-3-piperazin-1-il-benzofuran,There are others A pharmaceutical composer was also mentioned These compounds regulate 5-HT6 serum receptors and can be used to treat cognitive disorders, such as Alzheimer's disease, such as schizophrenia, anorexia, bulimia and other eating converters.
机译:式(I)或(I)的除草剂或同型除草剂衍生物,其中x是连接基或n-r4; R1是h或甲基; R 2为h或甲基; R3为h,C1-C3的焦油,氟等; R4为h,C1-C4焦油,C3-C4环丙基化合物等; R5是h,F,Cl,C1-C2焦油等。 R6为h,f或Cl; n为1或2。最受欢迎的是:n-(3-氯氟甲烷-苯基)-4-甲基-3-哌嗪-1-il-苯并呋喃,1-[5-(3-二氟甲烷-苯并呋喃)-2-甲基-苯基)盐酸盐,N-(4-二氟甲烷-苯基)-4-甲基-3-哌嗪-1-il-苯并呋喃,还有其他药物组合物也被提及这些化合物调节5-HT6血清受体并且可以用于治疗认知障碍,例如阿尔茨海默氏病,例如精神分裂症,厌食症,贪食症和其他饮食转变者。

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