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biological material suitable for the treatment of osteoarthritis of the damage of the ligament, and for treatment of diseases of the joints.

机译:生物材料,适合治疗韧带损伤的骨关节炎,以及治疗关节疾病。

摘要

The present invention regards a biological material comprising: a) a liquid carrier comprising a viscous solution containing at least one natural and/or semisynthetic polysaccharide, and having a Dynamic viscosity measured at 20° C. and at shear rate of D=350 s1, comprised between 100 and 250 c Poise and/or a Kinematic viscosity comprised between 99 and 248 cSt (measured at the same conditions); b) a culture of mesenchymal stem cells, and/or c) a platelet-rich hemo-derivative. This type of material in form of viscous liquid is particularly suitable for the therapy of osteoarthrosis, ligament damage, in particular tendon and cartilage damage) and may be administered intra-articularly, intradermally or directly applied in situ without altering the properties of the mesenchymal stem cells and/or platelets contained therein.
机译:本发明涉及一种生物材料,其包括:a)液体载体,其包含含有至少一种天然和/或半合成多糖的粘性溶液,并且具有在20℃和在D = 350 s1的剪切速率下测得的动态粘度,在100至250 cPoise之间和/或在99至248 cSt之间的运动粘度(在相同条件下测量); b)间充质干细胞的培养,和/或c)富含血小板的血液衍生物。这种类型的粘性液体形式的材料特别适合于治疗骨关节炎,韧带损伤,尤其是腱和软骨损伤),可以在不改变间充质干性质的情况下,通过关节内,皮内或直接就地给药其中所含的细胞和/或血小板。

著录项

  • 公开/公告号IT1394570B1

    专利类型

  • 公开/公告日2012-07-05

    原文格式PDF

  • 申请/专利权人 FIDIA FARMACEUTICI S.P.A.;

    申请/专利号IT2009MI01171

  • 发明设计人 ZANELLATO ANNA MARIA;CALLEGARO LANFRANCO;

    申请日2009-07-02

  • 分类号A61L27/20;A61K35/16;A61K35/19;A61K35/28;

  • 国家 IT

  • 入库时间 2022-08-21 17:22:16

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