use of sequences of amino acids from mycobacterium tuberculosis and their corresponding nucleic acids for the diagnosis and prevention of infection on tuberculosis, diagnostic kit and vaccine.

摘要

The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease.