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procedures for the quantification of micro rnas and small interference rna

机译:微量RNA和小干扰RNA的定量程序

摘要

The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.
机译:本发明涉及核糖核酸,用于检测,定量以及监测成熟微小RNA和小干扰RNA(siRNA)表达的探针和方法。本发明还涉及用于监测其他非编码RNA,mRNA剪接变体的表达以及检测和定量RNA编辑,单转录本的等位基因变体,转录本中特定外显子的突变,缺失或重复的方法,例如,与人类疾病(例如癌症)相关的变化。本发明还涉及用于检测,定量以及监测脱氧核酸表达的方法。

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