首页> 外国专利> COMPOSITION OF VACCINE AGAINST ALLERGY, PROCEDURE OF PRODUCTION OF THE SAME AND USE OF THE SAME IN THE TREATMENT OF ALLERGIES.

COMPOSITION OF VACCINE AGAINST ALLERGY, PROCEDURE OF PRODUCTION OF THE SAME AND USE OF THE SAME IN THE TREATMENT OF ALLERGIES.

机译:预防过敏的疫苗的组成,相同疫苗的生产过程以及在过敏治疗中的相同疫苗的使用。

摘要

The present invention relates to the field of Immunology, Immunoalergy and in particular the use of adjuvants or carriers to modulate the immune response to allergens. The technical objective is to obtain a pharmaceutical preparation for therapeutic or prophylactic use using bacterial proteoliposomes, which when applied in allergic individuals transforms the allergic response Th2 and IgE dependent, towards a protective Th1 response; as well as prevent the appearance and development of allergies in individuals not yet allergic. The vaccine composition consists of proteoliposomes of Gram-negative bacteria coupled to allergens and optionally other antigens or adjuvants. The method for obtaining it is provided and the 2 dose schedule for immunization with said vaccine composition is included.
机译:本发明涉及免疫学,免疫能学领域,尤其涉及佐剂或载体在调节对变应原的免疫应答中的用途。技术目标是获得使用细菌蛋白脂质体的用于治疗或预防用途的药物制剂,当将其用于过敏性个体时,其将过敏反应Th2和IgE依赖性转化为保护性Th1反应。并防止尚未过敏的人出现和发展过敏。疫苗组合物由与过敏原和任选的其他抗原或佐剂偶联的革兰氏阴性细菌的蛋白脂质体组成。提供了获得它的方法,并包括了用所述疫苗组合物进行免疫的2剂方案。

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