pure ceramic macroporous scaffold based on nanocrystalline apatite preparation method and applications.

摘要

pure ceramic macroporous scaffold based on nanocrystalline apatite preparation method and applications.; The invention describes a pure ceramic scaffold, nanocrystalline ceramic, wherein the ceramic comprises apatite unsubstituted or silicon-substituted apatite. Said scaffold combines excellent biocompatibility apatite, with improved bioactivity due to the presence of silicon, with the nanocrystalline structure of the ceramic, suitable for the tissue where it is intended to implement, and control of the macroporosity is achieved using the technique of rapid prototyping.; The invention also includes the method of preparation of the scaffold. This method comprises: preparation of the bioceramic, grinding bioceramics until a multimodal particle size, preparation of the ceramic ink in aqueous medium stabilized with a mixture consisting of a monomer component and a surfactant, making macroporous scaffold three-dimensional printing (3D) , consolidation and calcining the same.; The preferred purpose of this scaffold is applied as an implant for bone regeneration.