A COMPREHENSIVE METHYLOME MAP OF MYELOID AND LYMPHOID COMMITMENT FROM HEMATOPOIETIC PROGENITORS

摘要

Provided herein are differentially methylated regions (DMRs) of multipotent progenitor cells (MPPs) and oligopotent progenitor cells and methods of use thereof. The invention provides methods for detecting and analyzing alterations in the methylation status of DMRs in such progenitor cells as well as methods for differentiating such cells.