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TGF-BETA IN THE DEVELOPMENT OF CONVENTIONAL DENDRITIC CELLS AND USES THEREOF
TGF-BETA IN THE DEVELOPMENT OF CONVENTIONAL DENDRITIC CELLS AND USES THEREOF
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机译:TGF-BETA在常规树突状细胞发育中的用途及其用途
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摘要
The present invention relates to TGF-beta in the development of conventional dendritic cells and the production of IFN-lambda by such conventional dendritic cells. The invention also relates to corresponding therapeutic uses of TGF-β and of the specific dendritic cell type in the prevention and treatment of infectious diseases and cancer. The conventional dendritic cells according to the invention are CD8+ conventional dendritic cells (CD8+ cDCs) and equivalents thereof (eCD8+ cDCs) in mouse and human.
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