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METHOD FOR ENZYMATIC SYNTHESIS OF CHEMICALLY MODIFIED RNA
METHOD FOR ENZYMATIC SYNTHESIS OF CHEMICALLY MODIFIED RNA
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机译:化学修饰的RNA的酶法合成方法
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摘要
The present invention relates to a method for enzymatically synthesizing chemically modified RNA by using RNA-dependent RNA polymerases (RdRp), especially RdRps from viruses of the Caliciviridae family. The method of the present invention is particularly useful for preparing RNA molecules of increased stability especially with respect to RNA degradation, for example for in vivo applications. Further subject matter of the present invention relates to a kit for carrying out the enzymatic synthesis of the chemically modified RNA.
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