METHOD FOR ANALYZING AND PREDICTING RISK OF HEPATOCELLULAR CARCINOMA IN PATIENTS WITH CHRONIC HEPATITIS B

摘要

The present invention provides a kind of for analyzing and predicting the risk of hepatocellular carcinoma, candidate markers hepatocellular carcinoma by examining difference mutation predicts that precore/core X genes and hepatitis type B virus (HBV) gene develop in patient group and chronic hepatitis B patient group and hepatocellular carcinoma from chronic hepatitis B, select the combined prediction of the manufacturer, wherein mutation occurs with hepatocellular carcinoma statistically significant difference, weight is provided, Mathematical treatment is passed through for the risk of hepatocellular carcinoma and the prediction of selected label hepatocellular carcinoma, it analyzes and predicts that Risk of Hepatocellular Carcinoma calculates the label for whether using the end value according to mutant and the Weight prediction hepatocellular carcinoma presence or absence provided. According to the present invention, individual risk develops into hepatocellular carcinoma, it can predict to depend on carrier or patient about Chronic HBV carriers or with hepatopathy in advance, therefore be capable of providing necessary information, the optimization process of each patient and more effectively determining clinical guidelines and the processing each patient in direction.