O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders

摘要

The present invention relates to methods of alleviating and inhibiting a Iymphoproliferative disorder in a mammal, the method comprising administering one or more rapamycin derivatives (including rapamycin) to the mammal (see figure 8). Further, the invention provides a method for identifying agents which are useful for alleviating and inhibibing Iymphoproliferative disorders, as well as a method for identifying agents which are capable of inhibiting metastasis of lymphatic tumors in a mammal.