COMPOSITIONS FOR ADMINISTERING RIFALAZIL AND OTHER ANTI-TUBERCULOSIS AGENTS IN UNIT DOSAGE FORM FOR ORAL ADMINISTRATION

摘要

Pharmaceutical compositions including rifalazil, a surfactant, a lipophilic antioxidant, and one or more antibiotics selected from the group consisting of isoniazid, streptomycin, pyrazinamide, and ethambutol are provided in a single unit dosage form for oral administration. The compositions can be used to treat tuberculosis. By placing the multiple antibiotic agents in a single unit dosage form, patient compliance with otherwise complicated treatment regimens can be increased.