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YEAST WITH INCREASED BUTANOL TOLERANCE INVOLVING A MULTIDRUG EFFLUX PUMP GENE
YEAST WITH INCREASED BUTANOL TOLERANCE INVOLVING A MULTIDRUG EFFLUX PUMP GENE
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机译:涉及多药物外排泵基因的丁醇耐受性提高的酵母
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摘要
Increasing tolerance to butanol in yeast has been accomplished by decreasing activity of Pdr5p encoded by an endogenous PDR5 gene. A deletion mutation of the PDR5 gene led to improved growth yield in the presence of butanol. Yeast cells with reduced Pdr5p activity, or other multidrug resistance ATP-binding cassette transporter protein activity encoded by CDR1 or BFR1, and a butanol biosynthetic pathway may be used for improved butanol production
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