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Indole derivatives as CRTH2 receptor antagonists in combination with a second active ingredient

机译:吲哚衍生物作为CRTH2受体拮抗剂与第二种活性成分联合使用

摘要

Compound of formula I are antagonists of the PGD2 receptor, CRTH2, and as such are useful in the treatment and/or prevention of CRTH2-mediated diseases such as asthma in combination with a second active ingredient such as a leukotriene antagonist.
机译:式I的化合物是PGD 2受体CRTH 2的拮抗剂,因此与第二活性成分例如白三烯拮抗剂组合可用于治疗和/或预防CRTH 2介导的疾病例如哮喘。 <图像文件=“ IMGA0001.GIF” he =“ 67” imgContent =“ chem” imgFormat =“ GIF” wi =“ 76” />

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