NON-NATURAL AMINO ACID-PRODUCING STRAIN AND A METHOD FOR PREPARING THE NON-NATURAL AMINO ACIDS USING THE SAME

摘要

PURPOSE: A method for preparing non-natural amino acids using a strain is provided to effectively product glutamic acid and to simply obtain the natural amino acids.;CONSTITUTION: A Corynebacterium sp. recombinant strain for producing non-natural amino acids contains a gene encoding transaminase including aromatic transaminase, aspartate transaminase, or branched chain amino transferase. The Corynebacterium sp. strain includes Corynebacterium glutamicum, Corynebacterium acetoglutamicum, Corynebacterium acetoacidophilum, Corynebacterium thermoaminogenes, or Corynebacterium ammoniagenes. The non-natural amino acids include (S)-homophenylalanine, (2R,3S)-3-phenylisoserin, L-phosphinothricine, HAAE[2-(3-hydroxy-1-adamantyl)-(2S)-amino ethanoic acid], or L-tert-leucine.;COPYRIGHT KIPO 2013