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TRANSGENIC MOUSE FOR STUDYING EPHRIN-A5 GENE FUNCTION AND A METHOD FOR PREPARING THE SAME

机译:研究Ephrin-A5基因功能的转基因小鼠及其制备方法

摘要

PURPOSE: A method for preparing a transgenic mouse for studying ephrin-A5 gene function is provided to lose or reduce ephrin-A5 function.;CONSTITUTION: A recombinant expression vector contains: ephrin-A5 promoter; a reporter gene which is placed at the downstream of the promoter and has recombinant sequences at both ends and 3' regulatory sequence thereof; ephrin-A5-Fc gene which is placed at the downstream of the reporter gene and a 3' regulatory sequence of the gene; and an ephrin-A5 enhancer placed at the downstream of the ephrin-A5-Fc gene. The ephrin-A5 promoter contains a sequence of sequence number 2.;COPYRIGHT KIPO 2013
机译:目的:提供一种用于研究或缺失ephrin-A5功能的转基因小鼠的方法,以研究ephrin-A5基因的功能。报道基因,其位于启动子的下游,并且在两端具有重组序列及其3'调节序列。 ephrin-A5-Fc基因,位于报告基因的下游和该基因的3'调控序列; ephrin-A5增强子位于ephrin-A5-Fc基因的下游。 ephrin-A5启动子包含2号序列; COPYRIGHT KIPO 2013

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