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METHOD FOR DIAGNOSING INFLAMMATORY DISEASES THROUGH ANALYSIS OF PROTEIN OR GENE OF EXTRACELLULAR VESICLE IN A BODY FLUID
METHOD FOR DIAGNOSING INFLAMMATORY DISEASES THROUGH ANALYSIS OF PROTEIN OR GENE OF EXTRACELLULAR VESICLE IN A BODY FLUID
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机译:通过体液中细胞外蛋白和基因分析诊断炎症性疾病的方法
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摘要
PURPOSE: A method for diagnosing inflammatory diseases and a diagnosis kit are provided to improve diagnosis accuracy. CONSTITUTION: A method for diagnosing inflammatory diseases comprises: a step of isolating cell adhesion proteins in fluid into water soluble protein fraction and extracellular endoplasmic reticulum fraction; and a step of quantitating proteins in the water soluble protein fraction and extracellular endoplasmic reticulum fraction. The proteins contain ICAM-1(intercellular adhesion molecule-1), E-selectin, and VCAM-1(vascular cell adhesion molecule-1). A method for diagnosing inflammatory diseases comprises a step of measuring the expression level of gene existing in the extracellular endoplasmic reticulum of body fluid. The cell adhesion protein is ICAM-1, E-selectin, and VCAM-1. [Reference numerals] (AA,EE) Cell culture liquid; (BB) Ultracentrifugation; (CC,FF) Soluble protein; (DD,GG) Extracellular endoplasmic reticulum
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