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Method for diagnosing inflammatory diseases through analysis of protein or gene of extracellular vesicle in a body fluid

机译:通过分析体液中细胞外囊泡的蛋白质或基因诊断炎性疾病的方法

摘要

The present invention relates to a method for diagnosing an inflammatory disease by separating a cell adhesion protein into a water soluble protein form and a membrane protein form contained in an extracellular endoplasmic reticulum and then analyzing each type of cell adhesion protein in terms of quantification and / . In addition, the present invention provides an inflammatory disease diagnostic kit or the like, characterized by measuring the abundance and / or the abundance ratio of the cell adhesion protein in the body fluids by the form. The diagnosis method of the present invention further improves the usability as a diagnostic marker of inflammatory diseases and the accuracy of diagnosis by performing a subdivision quantification by adding another analytical factor called " presence form " It is expected to be possible.
机译:本发明涉及一种用于诊断炎性疾病的方法,其通过将细胞粘附蛋白分离成细胞外内质网中包含的水溶性蛋白形式和膜蛋白形式,然后根据定量和/或分析每种类型的细胞粘附蛋白来进行。 。另外,本发明提供了一种炎性疾病诊断试剂盒等,其特征在于通过该形式测量体液中细胞粘附蛋白的丰度和/或丰度比。本发明的诊断方法通过添加称为“存在形式”的另一种分析因子进行细分定量,进一步提高了作为炎性疾病的诊断标志物的可用性和诊断的准确性,预期是可能的。

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