METHOD FOR DIAGNOSING OF RESPIRATORY INFLAMMATORY DISEASES USING BACTERIA-DERIVED EXTRACELLULAR VESICLES

摘要

The present invention relates to a method for diagnosing respiratory inflammatory diseases by using a bacteria-derived extracellular endoplasmic reticulum and, more specifically, to a method for providing information for diagnosing asthma, chronic obstructive lung diseases, and lung cancer by measuring an antibody specific to an extracellular endoplasmic reticulum derived from bacteria existing in indoor dust or to a protein derived from the endoplasmic reticulum. An extracellular endoplasmic reticulum derived from Staphylococcus, Acinetobacter, Pseudomonas, and Enterobacter sp. bacteria massively existing in dust of indoor air may cause respiratory inflammatory diseases. Accordingly, the method according to the present invention can be useful as a method for diagnosing asthma, chronic obstructive lung diseases, and lung cancer by measuring an antibody specific to an extracellular endoplasmic reticulum/protein derived from the bacteria in a patient sample.