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STEM CELLS HAVING IMPROVED KIDNEY SPECIFIC HOMING AND THERAPEUTIC COMPOSITIONS COMPRISING THE CELLS

机译:干细胞具有改善的肾脏特定归巢和组成细胞的治疗成分

摘要

PURPOSE: A stem cell which increases mobility specifically towards the kidney and a composition for treating kidney diseases including the same are provided to increase cytotherapy efficiency of kidney for multiple organ failure patients. CONSTITUTION: A composition for treating kidney diseases includes stem cells which specifically increase mobility towards kidney. The kidney disease is multiple organ failure including kidney, acute or chronic renal failures. The stem cell which increases mobility specifically towards the kidney increases the expression of a chemokine receptor by treating TNF- A to the stem cell. The stem cell is obtained by treating KIM-1 and increasing mobility to inside the kidney.
机译:用途:提供一种干细胞,该干细胞能特异性地增加对肾脏的运动能力,并提供了一种用于治疗肾脏疾病的组合物,以提高多器官功能衰竭患者肾脏的细胞治疗效率。组成:一种用于治疗肾脏疾病的组合物,包括干细胞,这些干细胞会特别增加对肾脏的运动能力。肾脏疾病是多器官衰竭,包括肾脏,急性或慢性肾衰竭。通过向干细胞处理TNF-A,特异性地增加了向肾脏的运动性的干细胞增加了趋化因子受体的表达。干细胞是通过治疗KIM-1并增加向肾脏内部的移动性而获得的。

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