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A gene CaLAG1 related to the yeast-to-hypha morphological transition and virulence in Candida albicans

机译：CaLAG1基因与白色念珠菌中的酵母菌到菌丝的形态转变和毒力有关

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摘要

The present invention relates to a novel gene related to the yeast-to-hypha morphological transition and pathogenicity of Candida albicans , a pathogenic strain causing candidiasis, and more particularly, Candida albicans. The discovery of a novel gene CaLAG1 involved in heterozygous and reveals its function in heteromorphism and pathogenicity. Therefore, the novel gene CaLAG1 or protein CaLag1p identified according to the present invention can be used as a target gene or target protein for screening antifungal substances that inhibit the pathogenicity of Candida albicans.;Candida albicans, CaLAG1, target gene, pathogenic, antifungal

机译：本发明涉及一种新的基因，该基因与引起念珠菌病，尤其是白色念珠菌的致病菌株白念珠菌的从酵母到菌丝的形态转变和致病性有关。发现了一个新的涉及杂合子的基因 CaLAG1 ，并揭示了其在异质性和致病性中的功能。因此，根据本发明鉴定的新基因 CaLAG1 或蛋白质CaLag1p可用作筛选抑制白色念珠菌致病性的抗真菌物质的靶基因或靶蛋白质。靶基因病原抗真菌 展开▼

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公开/公告号KR101102667B1

专利类型

公开/公告日2012-01-05

原文格式PDF

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申请/专利号KR20040028338

发明设计人 김정윤;전선아;이병규;김종균;최정식;강희일;
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申请日2004-04-23

分类号C12N15/31;

国家 KR

入库时间 2022-08-21 17:08:48

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1. Candida albicans isolated from urine: Phenotypic and molecular identification, virulence factors and antifungal susceptibility [J] . Laura Wiebusch, Bruna de Paula Bicudo, Danielle Ferreira Lonchiati, 亚太热带生物医学杂志（英文版） . 2017,第007期

2. Candida albicans isolated from urine: Phenotypic and molecular identification, virulence factors and antifungal susceptibility [J] . Laura Wiebusch, Adriana Araújo de Almeida-Apolonio, Luana Mireli Carbonera Rodrigues, 亚太热带生物医学杂志：英文版 . 2017,第007期

3. Inhibition of Yeast-to-Hypha Transition and Virulence of Candida albicans by 2-Alkylaminoquinoline Derivatives [J] . Meng Lili, Zhao He, Zhao Shuo, Journal of neurosurgical sciences . 2019,第4期

4. Inhibition of Yeast-to-Hypha Transition and Virulence of Candida albicans by 2-Alkylaminoquinoline Derivatives [J] . Meng Lili, Zhao He, Zhao Shuo, Antimicrobial agents and chemotherapy. . 2019,第4期

5. The serine/threonine protein phosphatase SIT4 modulates yeast-to-hypha morphogenesis and virulence in Candida albicans [J] . Lee CM., Nantel A., Jiang LH., Molecular Microbiology . 2004,第3期

6. Inhibition of pathogenically-related morphologic transition in Candida albicans by disrupting Cdc42 binding to its effectors [C] . Hongjian Li, Yang Li, Feng Ni American Peptide Symposium . 2009

7. The role of the cyclic AMP-signaling pathway in morphogenic transitions, resistance to stresses, and virulence of Candida albicans. [D] . Bahn, Yong-Sun. 2003

8. Inhibition of Yeast-to-Hypha Transition and Virulence of Candida albicans by 2-Alkylaminoquinoline Derivatives [O] . Lili Meng, He Zhao, Shuo Zhao, 2019

9. The serine/threonine protein phosphatase SIT4 modulates yeast-to-hypha morphogenesis and virulence in Candida albicans [O] . Lee, Chang-Muk, Nantel, Andrue9, Jiang, Linghuo, 2004

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2. Nocvel potential targets and related genes of transcription factor Caplp in Candida albicans 1 [J] . YahWANG ,Yong-bingCAO ,Xin-mingJIA . 中国药理通讯 . 2005,第002期

3. Effect of Growth Media, pH and Temperature on Yeast to Hyphal Transition in iCandida albicans/i [J] . Sayyada Ghufrana Nadeem ,Amna Shafiq ,Shazia T. Hakim . 医学微生物学（英文） . 2013,第3期

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5. MDR1基因与白色念珠菌毒力相关性及药物联用治疗感染小鼠的研究 [A] . 李航 . 2015