Formula I 3- unsubstituted, 3-substituted or 3,3-disubstituted 9-il Fig acyloxy-1,5-dihydro-8-methyl-pyrido of [3,4-e] [1,3] dioxepine and optionally, the method of manufacture is pyridoxine, solvent and formula II of the 4-methyl-5-alkoxy, under substantial absence of catalyst-oxazole of the formula III 2-unsubstituted, 2-monosubstituted or 2,2-disubstituted 4, 7-dihydro- (1, 3) - by the addition reaction dioxepine, a large amount of a suitable di (IV) Els-Alder adduct and a small amount of the appropriate 3-unsubstituted of formula V, 3-mono- or 3,3 -disubstituted 1,5-dihydro-8-methyl-pyrido produce a product mixture consisting of [3,4-e] [1,3] dioxepine-9 come into and essentially, unreacted from the product mixture by distillation under reduced pressure oxazole and dioxane substantially removed sepin starting material and then, (IV) adding a substantial anhydrous organic acid to the product mixture, while removing the all produced by distillation under reduced pressure to alkane in the presence of the substantially anhydrous organic acid Diels- Alder addition and by arranging the water re-produce the compound of formula V of the additional and, as a result, to produce the compounds of formula (I) in which more ah widening a carboxylic acid anhydride is added to the compound of formula V in the amount of a misfire by the purpose, optionally with this by achieving the deprotection and deacylation by acid hydrolysis of the acylated product of the formula I is manufactured it includes a switch Sikkim as pyridoxine. Pyridoxine is a well known form of vitamin B 6 The purpose is widely established.
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