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Method of preparing ß-sustituted chiral g-lactol,g-lactone and 3-substituted chiral tetrahydrofurane and chiral g-lactol, g-lactone and chiral tetrahydrofurane prepared by thereof
Method of preparing ß-sustituted chiral g-lactol,g-lactone and 3-substituted chiral tetrahydrofurane and chiral g-lactol, g-lactone and chiral tetrahydrofurane prepared by thereof
The invention of optically active substituted beta gamma position - raktol, gamma-lactone and 3-position The method for producing a tetrahydrofuran substituted optically active and whereby the activity of the produced gwanghwak gamma-raktol, gamma-lactone, and relates to the tetrahydrofuran, the beta position is substituted with an optically active gamma-production method of raktol is indole, pyrrole, or amine group substituted benzene gamma-hydroxy-alpha, beta-1, 4-addition reaction and a catalyst for the reaction step in the presence of a chiral catalyst to an unsaturated aldehyde amine The method is simple and easy process than the conventional number of the optically active beta-position is substituted to be used as an intermediate in the synthesis of the substance gamma-lactone and the 3-position can be obtained in a tetrahydrofuran substituted with a high yield of optically active . In addition, by using the heavy metal catalysts of the organic compound itself to easy process without using a catalyst and does not require a separate step of removing heavy metal catalyst.
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