Composition for ameliorating the ER stress or the mitochondrial dysfunction comprising the extract of Angelica dahurica or imperatorin

摘要

PURPOSE: A pharmaceutical containing Angelica dahurica extract or imperatorin as an active ingredient is provided to prevent or treat diseases caused by endoplasmic reticulum stress or mitochondria malfunctions. CONSTITUTION: A medicinal composition for preventing or treating diseases caused by endoplasmic reticulum stress or mitochondria malfunction contains Angelica dahurica extract or imperatorin. The diseases are liver fibrosis, metabolic syndrome, hypertension, neurodegenerative disorder, bipolar disorder, diabetes, artery scleroma, and ischemia. A medicinal formulation contains the medicinal composition and is used in the form of a tablet, oral tablet, liquids, jelly, aqueous or oil suspension, dispersion powders, or granules, emulsion, soft or hard capsule, or syrup.