NEW LACTOBACILLUS PARACASEI SUBSPECIES PARACASEI STRAIN WITH ANTIMICROBIAL AND IMMUNOMODULATING PROPERTIES

摘要

1. The strain of Lactobacillus paracasei subsp. paracasei having antimicrobial and immunomodulating properties, characterized in that it is a strain deposited in CNCM under the number I-3689. ! 2. The strain of Lactobacillus paracasei subsp. paracasei having antimicrobial and immunomodulating properties, characterized in that it can be obtained from the strain according to claim 1 by mutagenesis or genetic transformation and in that it has antimicrobial and immunomodulating properties of CNCM strain I-3689 and / or has a CRISPR locus of SEQ sequence ID NO: 1. ! 3. A method of obtaining a strain of Lactobacillus paracasei subsp. paracasei having antimicrobial and / or immunomodulating properties, characterized in that it includes a mutagenesis or genetic transformation stage of the CNCM strain I-3689. !four. A method of obtaining a cell fraction having antimicrobial and / or immunomodulating properties, characterized in that said cell fraction is obtained from a strain of Lactobacillus paracasei subsp. paracasei according to any one of claims 1 and 2.! 5. The method according to claim 4, characterized in that said cell fraction is selected from the group consisting of a DNA preparation, a bacterial wall preparation, a culture supernatant and a fraction of said supernatant. ! 6. A method of obtaining a composition with antimicrobial and immunomodulatory properties, characterized in that it includes obtaining a cell fraction by the method according to any one of claims 3 and 4 and the inclusion of the specified fraction in the specified composition. ! 7. The method according to claim 6, characterized in that said product is a food product. ! 8. A composition comprising a strain of Lactobacillus paracasei subsp. paracasei according to any one of claims 1 and 2, or a cell fraction obtained by the method defined in any of claims 4 and 5.