1. The method of filling two-chamber systems (3) in a pre-sterilized carrier system (1), characterized in that it contains the following stages:! - preparation of at least one washed and sterilized two-chamber system (3) with separating element (7) from each other both chambers (5, 5 ') in the holder (9), which receives at least one two-chamber system (3), moreover, the holder (9) is located in a vessel (11) closed by means of a closing element (13); ! - input of the vessel (11) through the lock into a clean room; ! - opening the vessel (11) and filling the first chamber (5) of at least one two-chamber system (3); ! - closing the first chamber (5) of at least one two-chamber system (3) with a gas-permeable closing element (19); ! - freeze drying contained in the first chamber (5) of at least one two-chamber system (3) of the solution (L1); ! - closing the first chamber (5) of at least one two-chamber system (3) with a closing element (19); ! - filling the second chamber (5 ') of at least one two-chamber system (3); ! - closing the second chamber (5 ') of at least one two-chamber system (3); ! - output through a gateway from a clean room. ! 2. The method according to claim 1, characterized in that the clip (9) contains plastic, preferably made of plastic. ! 3. The method according to claim 1 or 2, characterized in that the vessel (11) contains plastic, preferably made of plastic. ! 4. The method according to claim 3, characterized in that the plastic is elastically deformable. ! 5. The method according to claim 1, characterized in that the clip (9) after closing the first chamber (5) and before filling the second chamber (5 ') of at least one two-chamber system (3) is turned over. ! 6
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